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apalutamide will decrease the extent or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with medication that happen to be CYP2C19 substrates may end up in decreased publicity to those remedies.diazepam raises amounts of lomitapide